Karl Landsteiner Gesellschaft

Institute for Neurochemistry, Neuropharmacology, Neurorehabilitation and Pain Therapy

Institute head
Work at the Institute

The institute's research focuses on neurochemistry and tryptophan metabolism in neuroinflammatory (e.g., multiple sclerosis, Lyme disease, and AIDS) and neurodegenerative (e.g., Alzheimer's and Parkinson's) diseases, as well as epilepsy. Experimental studies on the aging process examine possible changes in mitochondrial function related to the influence of tryptophan metabolites. Epilepsy studies examine changes in prostaglandins, catecholamines, serotonins, and neuronal markers of the GABA and cholinergic systems, as well as kynurenine metabolism. These studies use a kainic acid animal model of temporal lobe epilepsy in humans. In the field of neuropsychopharmacology, the institute aims to further clarify the mechanisms of action of anti-dementia and anti-epileptic substances.